Pisa and Firenze are about one hour driving, You can easily go there for a day trip. You can easily go also to one of the most beautiful Tuscany city as Lucca, where you can have a nice walk and visit the many historycal churces ( S.Michele church in the picture)
Siena is about two hours driving, but you can choose to have a nice week end there, the guest can give you all the needed informations for streets, guest houses and restaurant.
In the picture Marina di Carrara shores, at forty minutes driving from Casa Sbarra. You can see on the back the Apuan Alps (the white you can see on top of the mountains is the Marble).
you can reach the Cinque Terre shores in almost half an hour driving. There you can also taste typical Ligurian plates and traditional wine.